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Thomas Kirkwood
University of Newcastle
School of Clinical Medical Sciences Gerontology
Henry Welcome Laboratory for Biogerontology Research
Newcastle General Hospital
Newcastle, United Kingdom |
Research
interests and relevant experience of responsible scientist
28
years in research on: evolution of ageing and longevity, interspecies
studies of cell stress resistance and longevity, stem cell ageing,
mitochondrial mutation in ageing, and computational network models
of ageing processes. Previously: Chair of British Society for
Research on Ageing, Chair of UK Government Foresight Taskforce
on Healthcare of Older People.
Currently:
Co-Editor, Mechanisms of Ageing and Development, European President
(Biology) of International Association of Gerontology, Council
Member of UK Biotechnology and Biological Research Council (funding
major initiatives on biology of ageing), and Council Member of
UK Academy of Medical Sciences. Tom Kirkwood is or has been a
participant in the past EU Concerted Actions EURAGE and MOLGERON
(FP4) and current Integrated Project GEHA and Coordination Action
LINK-AGE (FP6). He has been the organizer of major conferences
including British Congress of Gerontology (1996) and the Gordon
Conference on Biology of Ageing (1998).
Tom
Kirkwood is also a scientific consultant for the industry in the
area of healthy ageing and he has extensive experience of research
dissemination to scientists, general public, and stakeholder groups,
including: award-winning popular science book Time of Our Lives:
The Science of Human Ageing (translated into Spanish, German,
Portuguese, Japanese, Chinese), and highly prestigious annual
BBC Reith Lectures (see www.bbc.co.uk/radio4/reith2001).
Staff
Tom
Kirkwood, Professor of Medicine and Head of Gerontology
Thomas von Zglinicki, Professor of Cellular Gerontology
David Lydall, Professor in Biology of Ageing
Norman McKie, Reader in Molecular Pathology
Gabriele Saretzki, Lecturer in Genome Instability
Marie-Laure Muiras, Technology Transfer Officer
Joanna Collerton, Senior Clinical Research Fellow, Healthy ageing
Carmen Martin-Ruiz, Research fellow, Genome Instability
Carole Proctor, Research fellow; BASIS modelling team
Daryl Shanley, Research fellow; BASIS modelling team
Colin Gillespie, Research fellow; BASIS modelling team
Bob Nicholson, Laboratory superintendent
6 PhD students and 4 research technicians in various areas of
biogerontology
Relevant
publications
Drenos
F, Westendorp RG, Kirkwood TB. Trade-off Mediated Effects on the
Genetics of Human Survival Caused by Increasingly Benign Living
Conditions. Biogerontology 2006; [Epub ahead of print]
Gillespie
CS, Wilkinson DJ, Proctor CJ, Shanley DP, Boys RJ, Kirkwood TB.
Tools for the SBML Community. Bioinformatics 2006; 22:628-9.
Kirkwood
TB. Time of our lives. What controls the length of life? EMBO
Rep 2005; 6 Spec No:S4-8
Kirkwood
TB. Food restriction, evolution and ageing. Mech Ageing Dev 2005;
126:1011-6
Kirkwood
TB. Understanding the odd science of aging. Cell 2005; 120:437-47
Proctor
CJ, Soti C, Boys RJ, Gillespie CS, Shanley DP, Wilkinson DJ, Kirkwood
TB. Modelling the actions of chaperones and their role in ageing.
Mech Ageing Dev 2005; 126:119-31.
Drenos
F, Kirkwood TB. Modelling the disposable soma theory of ageing.
Mech Ageing Dev 2005; 126:99-103.
Ishizuka
S, Martin K, Booth C, Potten CS, de Murcia G, Burkle A, Kirkwood
TB. Poly(ADP-ribose) polymerase-1 is a survival factor for radiation-exposed
intestinal epithelial stem cells in vivo. Nucleic Acids Res 2003;
31:6198-205.
Kirkwood
TBL, Boys RJ, Gillespie CS, Proctor CJ, Shanley DP, Wilkinson
DJ. Towards an e-biology of ageing: integrating theory and data.
Nat Rev Mol Cell Biol 2003; 4: 243-9.
Proctor
CJ, Kirkwood TBL. Modelling telomere shortening and the role of
oxidative stress. Mech Ageing Dev 2002; 123:351-63.
von
Zglinicki T, Bürkle A, Kirkwood TBL. Stress, DNA damage and
ageing - an integrative approach. Exp Gerontol 2001; 36:1049-62.
Kirkwood
TBL, Austad SN. Why do we age? Nature 2000; 408:233-38.
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